Table 2 Baseline spirometry of the UPLIFT^® study population according to quartiles of RoD in post-bronchodilator FEV₁.

FEV ₁ (L)

   Pre-bronchodilator

1.11 ± 0.40

1.06 ± 0.40

1.09 ± 0.39

1.21 ± 0.39

   Post-bronchodilator

1.33 ± 0.44

1.28 ± 0.44

1.32 ± 0.44

1.47 ± 0.42

FEV ₁ (% predicted)

   Pre-bronchodilator

39.7 ± 12.1

39.1 ± 12.0

39.3 ± 12.1

41.4 ± 11.3

   Post-bronchodilator

47.6 ± 12.7

47.3 ± 12.8

47.8 ± 12.6

50.0 ± 11.5

FEV ₁ (% increase)*

22.6 ± 18.7

23.7 ± 17.4

24.1 ± 17.9

23.2 ± 18.2

FVC (L)

   Pre-bronchodilator

2.56 ± 0.81

2.51 ± 0.81

2.62 ± 0.79

2.92 ± 0.79

   Post-bronchodilator

2.99 ± 0.87

2.97 ± 0.86

3.10 ± 0.83

3.42 ± 0.86

FVC (% predicted)

   Pre-bronchodilator

72.7 ± 17.6

73.6 ± 17.6

75.2 ± 18.1

79.0 ± 17.3

   Post-bronchodilator

84.9 ± 18.7

87.2 ± 18.3

89.1 ± 19.1

92.7 ± 17.9

GOLD stage (%)

   II

45

46

45

54

   III

44

43

45

40

   IV

9

10

8

4