Protease-activated receptor 2 activation of myeloid dendritic cells regulates allergic airway inflammation

Respiratory Research

Table 1 Differential cell count in BAL fluid of wild type and PAR-2-deficient mice.

	Mac	Epi	Eos	Neut	Lymph
BALB/c PBS	1.4 ± 0.2	1.7 ± 0.4	0	0.04 ± 0.02	0.09 ± 0.05
PAR2-/- PBS	1.6 ± 0.3	3.5 ± 1.6	0	0.02 ± 0.02	0.07 ± 0.03
BALB/c frass	8.6 ± 3.6	5.2 ± 1.6	1.7 ± 0.5	4.4 ± 0.7 *	1.6 ± 0.04
PAR2-/- frass	3.4 ± 1.1	4.0 ± 1.5	0.6 ± 0.3 †	1.2 ± 0.02 †	1.5 ± 0.8

BALB/c and PAR-2-/- mice were challenged by intratracheal inhalation on Day 0 and 14 with PBS or GC frass (40 μg). On day 17, BAL fluid was harvested and differential cell counts performed. These data represent 4-6 mice per group and are expressed as mean ± SEM of cell number × 10³. Cell counts were statistically significant between GC frass and PBS exposed mice (*p < 0.05) and between BALB/c and PAR-2-/- mice (†p < 0.05).

ISSN: 1465-993X