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Figure 8 | Respiratory Research

Figure 8

From: Overexpression of sICAM-1 in the Alveolar Epithelial Space Results in an Exaggerated Inflammatory Response and Early Death in Gram Negative Pneumonia

Figure 8

In vitro stimulation of AM with LPS and recombinant sICAM-1 results in a synergistic increase in TNFα and MIP-2 production from AM. AM isolated by whole lung lavage from normal wild-type mice were stimulated with LPS (100 μg/ml) and/or recombinant sICAM-1 (50 μg/ml). Both TNFα (A) and MIP-2 (B) were measured by ELISA of cell culture supernatant after a 24 hour incubation. Data are expressed as mean ± SEM. (n = 6 for all groups; * P < 0.05 compared to all other conditions).

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Respiratory Research

ISSN: 1465-993X

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