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Figure 3 | Respiratory Research

Figure 3

From: Overexpression of sICAM-1 in the Alveolar Epithelial Space Results in an Exaggerated Inflammatory Response and Early Death in Gram Negative Pneumonia

Figure 3

Overexpression of sICAM-1 in the distal lung results in decreased survival after K. pneumoniae infection. SPC-sICAM-1 mice and wild-type controls were inoculated intranasally with 2500 CFU of K. pneumoniae on day 0 and the percentage of mice surviving was determined over time. At 10 days, survival was significantly decreased in the SPC-sICAM-1 mice compared with infected wild-type controls. * P = 0.0012 compared with wild-type control mice.

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Respiratory Research

ISSN: 1465-993X

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