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Figure 2 | Respiratory Research

Figure 2

From: Pseudomonas aeruginosa toxin ExoU induces a PAF-dependent impairment of alveolar fibrin turnover secondary to enhanced activation of coagulation and increased expression of plasminogen activator inhibitor-1 in the course of mice pneumosepsis

Figure 2

ExoU-induced procoagulant activity in mice airways. Tissue factor dependent procoagulant activity was significantly increased in BALF from PA103-infected mice. ** p < 0,01 and *** p < 0,001 when mice infected with PA103 (n = 12) were compared with those infected with the bacterial mutant (n = 10) or with control mice (n = 10). Data represent mean values ± SE of the results obtained in three different assays.

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