Figure 7
Cytotoxic NK Cell Activity is Suppressed in Smokers Following LAIV. Cytotoxic NK cell percentages and activity were analyzed in NLF of nonsmokers and smokers after LAIV inoculation. A) CD16+ cytotoxic NK cell percentages of total NK cells were decreased in the NLF of smokers following LAIV. Kruskal-Wallis p = 0.09, *p < 0.05 nonsmoker vs smoker posttest. Nonsmokers n = 12 (â– , solid line), smokers n = 9 (â–², dashed line). B) Granzyme B activity was decreased in NLF of smokers following LAIV inoculation. Kruskal-Wallis p < 0.01, *p < 0.05 nonsmoker vs smoker post-test. Nonsmokers n = 13 (â– , solid line), smokers n = 13 (â–², dashed line).