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Table 1 Lung Inflammatory parameters at Commencement of Drug Treatment

From: Histamine H4 receptor antagonism diminishes existing airway inflammation and dysfunction via modulation of Th2 cytokines

  

BALF Cells (×106)

 

Lung Cytokines

(pg/μg protein)

 

WBCs

Macs

Eos

Neuts

Lymph

IL-5

IL-13

Saline

0.35 ± 0.05

0.35 ± 0.05

0

0

0

BLLOQ

0.01 ± 0.003

OVA

1.85 ± 0.10

0.79 ± 0.06

0.48 ± 0.07

0.57 ± 0.05

0.005 ± 0.004

0.35 ± 0.05

1.24 ± 0.15

  1. Definition of Abbreviations: BALF = bronchoalveolar lavage fluid; BLLOQ = below lower limit of quantification; eos = eosinophils; OVA = ovalbumin; WBCs = white blood cells. Values represent mean ± SEM