Table 6 Negative binomial regression analysis of relationship between exacerbation rates over the one year follow up period and sputum neutrophil percentage at baseline.
From: Sputum neutrophils as a biomarker in COPD: findings from the ECLIPSE study
| Â | Single Dependent | Multiple Dependents | ||||
|---|---|---|---|---|---|---|
Independent Variables in Model | Incidence Rate Ratio | 95% CI | p-value | Incidence Rate Ratio | 95% CI | p-value |
Age | 0.99 | (0.98,1.00) | 0.173 | 0.99 | (0.98,1.01) | 0.370 |
BMI | 1.00 | (0.97,1.03) | 0.862 | 1.00 | (0.97,1.02) | 0.817 |
Concomitant ICS use | 2.02 | (1.47,2.76) | <0.001 | 1.75 | (1.29,2.37) | <0.001 |
Current smoking status | 0.98 | (0.76,1.28) | 0.903 | 0.94 | (0.73,1.20) | 0.605 |
Pack years | 1.00 | (0.99,1.00) | 0.732 | 1.00 | (1.00,1.01) | 0.817 |
FEV1 % predicted | 0.98 | (0.97,0.99) | <0.001 | 0.98 | (0.97,0.99) | <0.001 |
Gender | 1.17 | (0.90,1.52) | 0.237 | 1.38 | (1.06,1.81) | 0.017 |
Sputum neutrophil % | 1.00 | (0.99,1.01) | 0.568 | 0.99 | (0.99,1.00) | 0.127 |