Table 3 Cellular populations in sputum of HNS, smokers and COPD subjects (median, range)
From: Enhanced effector function of cytotoxic cells in the induced sputum of COPD patients
| Â | HNS (group A, n = 5) | Smokers (group B, n = 10) | COPD Subjects (group C, n = 11) | p values |
|---|---|---|---|---|
TCC, × 107 cells/g | 1.24 (0.4-1.9) | 4.93 (2-7.4) | 10.66 (5.2-14.9) | COPD vs Smokers p < 0.05 COPD vs HNS p < 0.001 |
Neutrophils, × 107 cells/g | 0.53 (0.14-0.63) | 2.37 (1.23-4.06) | 7.94 (3.82-12.13) | COPD vs Smokers p < 0.01 COPD vs HNS p < 0.001 |
Macrophages, × 107 cells/g | 0.58 (0.21-0.95) | 2.41 (0.88-3.99)) | 1.89 (0.76-2.75) | COPD vs HNS p < 0.05 Smokers vs HNS p < 0.01 |
Lymphocytes, × 107 cells/g | 0.01 (0.00-0.02) | 0.16 (0.04-0.51) | 0.90 (0.28-1.44) | COPD vs Smokers p < 0.05 COPD vs HNS p < 0.001 |
Eosinophils, × 107 cells/g | 0.009 (0.001-0.023) | 0.022 (0.002-0.056) | 0.122 (0.019-0.203) | NS |
Neutrophils, % | 35.3 (29.8-41.9) | 55.5 (38.1-67.2) | 74.2 (59.4-82.7) | COPD vs Smokers p < 0.01 COPD vs HNS p < 0.001 |
Macrophages, % | 51.4 (40.9-63.6) | 42.8 (35.5-62.4) | 19.6 (6.8-27.2) | COPD vs Smokers p < 0.001 COPD vs HNS p < 0.01 |
Lymphocytes, % | 0.9 (0.3-1.3) | 3.9 (0.7-7.4) | 9.5 (3.2-13.5) | COPD vs Smokers p < 0.05 COPD vs HNS p < 0.001 |
Eosinophils, % | 0.7 (0-1.2) | 0.6 (0.1-0.9) | 1.3 (0.2-1.9) | NS |