Figure 2From: PPARγ deficiency results in reduced lung elastic recoil and abnormalities in airspace distributionDistribution of lung elastic fibers. Hart's elastin stain was performed on inflated fixed lung tissue from 8 week old conditionally targeted (B, D, F) and littermate control (A, C, E) mice. Low magnification images (A, B) reveal elastin deposition most prominently in vascular (V) media and conducting airway (AW) walls. High magnification images (C-F) reveal elastin distribution at the terminus of the conducting airway wall (the bronchiole-alveolar duct junction; BADJ) and in the parenchyma, with fibers concentrated at the tips of alveolar septae (arrow).Back to article page