Figure 1
From: PPARγ deficiency results in reduced lung elastic recoil and abnormalities in airspace distribution
Lung elastic recoil. The relative and absolute contributions of surface tension (Pγ) and tissue recoil (Ptis) to lung elasticity (Pel) in conditionally targeted (KO; n = 8) (red) and littermate control (CTL; n = 8) (blue) mice were evaluated from air- and saline-filled pressure-vs-volume profiles. A, Absolute lung elasticity (Pel) measured as tissue recoil (Ptis) and surface tension (Pγ) are reduced in conditionally targeted mice. B, Proportion of lung elasticity resulting from surface tension corrected for lung volume is similar between conditionally targeted and littermate control mice. Error bars represent standard deviation.