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Figure 2 | Respiratory Research

Figure 2

From: Intracerebroventricular injection of leukotriene B4 attenuates antigen-induced asthmatic response via BLT1 receptor stimulating HPA-axis in sensitized rats

Figure 2

LTB 4 via i.c.v attenuates the antigen-induced increases of inflammatory cell in the BALF, and U75302 blocks the inhibitory effect of LTB 4 . Total inflammatory cells in BALF were counted, and cell classification was performed on a minimum of 200 cells to classify monocytes (lymphocytes and macrophages) and polymorphonuclear cells (eosinophils and neutrophils) 24 hr after the final antigen challenge. Data are expressed as the mean ± S.D. of vehicle-sham (n = 8), vehicle-OVA (n = 10), LTB4-OVA (n = 9), U75302-OVA (n = 9) and U75302-LTB4-OVA (n = 10). ##P < 0.01 vs the vehicle-sham group;**P < 0.01 vs the vehicle-OVA group; ††P < 0.01 vs the LTB4-OVA group.

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