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Table 4 Linear Regression Analysis (Quantification Langerin+ DC in small airways)

From: Selective accumulation of langerhans-type dendritic cells in small airways of patients with COPD

DC surface marker R2 Predictor Variable β p
Langerin+ DC in Total Airway Wall 0.23 FEV1(% pred) -0.436 0.002
   Age -0.088 0.441
   Gender 0.186 0.105
   Packyear 0.065 0.592
   Smoking status 0.011 0.920
   Inhaled CS 0.006 0.968
   Oral CS 0.047 0.705
Langerin+ DC in Epithelium 0.20 FEV1(% pred) -0.398 0.006
   Age -0.049 0.674
   Gender 0.130 0.264
   Packyear 0.031 0.805
   Smoking status 0.090 0.427
   Inhaled CS 0.019 0.898
   Oral CS 0.046 0.715
Langerin+ DC in Lamina Propria 0.16 FEV1(% pred) -0.350 0.018
   Age -0.076 0.525
   Gender 0.160 0.179
   Packyear 0.111 0.381
   Smoking status 0.078 0.503
   Inhaled CS -0.093 0.542
   Oral CS 0.125 0.336
Langerin+ DC in Adventitia 0.40 FEV1(% pred) -0.434 0.001
   Age 0.045 0.673
   Gender 0.217 0.039
   Packyear -0.028 0.799
   Smoking status 0.115 0.271
   Inhaled CS 0.187 0.176
   Oral CS 0.072 0.542
  1. Abbreviations: DC: dendritic cell; FEV1(% pred): forced expiratory volume in one second (% predicted); CS: corticosteroids.
  2. β:standardized coefficient. Smoking status: current versus non-current smoker
  3. Significant p values are marked in bold.