Bleomycin-induced pulmonary fibrosis is enhanced inNrf2-/-mice. (A) Representative photographs of lungs from WT mice and Nrf2-/- mice 28 days after treatment with bleomycin (bleo) or saline. Magnification: ×40. (B-C) The score of fibrosis (B) and lung hydroxyproline contents (C) of WT mice (open bars) and Nrf2-/- mice (solid bars) 28 days after treatment with bleomycin (bleo) or saline. n = 6 in each group.*Significant difference (p<0.05) between WT mice and Nrf2-/- mice.