Figure 2

Oral tolerance improves inspiratory and expiratory parameters. Time of inspiration (A), time of expiration (B), peak inspiratory flow rate (C) and Peak expiratory flow rate (D) were measured in CRA fed and PBS fed mice 4 hours after final CRA challenge. Data were recorded for 5 minutes in response to 50 mg/mL of methacholine. Each value is the mean ± SEM for n = 18. * = p < 0.05 and ** = p < 0.01 comparing CRA fed to PBS fed mice.