Figure 8
From: Modulation of cytokine and nitric oxide by mesenchymal stem cell transfer in lung injury/fibrosis
Effect of bone marrow-derived mesenchymal stem cell (BMDMSC) transfer on the levels of IL-6 and TNF-α in bronchoalveolar lavage fluid and IL-1β, vascular endothelial growth factor (VEGF), and TGF-β in lung lysates. Bleomycin treatment significantly increased the levels of IL-1β (A), VEGF (B), IL-6 (C), TNF-α (D), and TGF-β (E) between days 7 and 28. The increases in IL-1β, VEGF, IL-6, TNF-α and TGF-β were significantly reduced by the transfer of BMDMSCs. * and ** indicate p < 0.05 and p < 0.01, respectively.