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Figure 8 | Respiratory Research

Figure 8

From: Dimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma

Figure 8

Effects of Cl 2 exposure and DMTU treatment on glutathione levels in BAL fluid and cells. (A) 10 minutes following Cl2 exposure, GSH levels in the BAL cell fraction show a significant increase that was attenuated by pre-treating the mice with DMTU one hour prior to Cl2 challenge. (B) 10 minutes following Cl2 challenge, the same significant increase of GSH is seen in the BAL supernatant. (C) GSH levels 1 hour following Cl2 exposure and (D) 24 hours after Cl2 exposure were not different among groups. (n = 6-9; * p < 0.05, **p < 0.01, ***p < 0.001).

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