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Table 1 Treatment Duration and Time to Peak FEV1 Measure

From: Assessing time to pulmonary function benefit following antibiotic treatment of acute cystic fibrosis exacerbations

 

Mean, days ± SD

Median, days

Range, days (min - max)

Interquartile Range, days

Antibiotic Treatment Duration

    

All patients (n = 95)

12.6 ± 3.2

13

23 (4 - 27)

3

ceftaz/tobra treated (n = 50)

12.5 ± 2.8

12.5

12 (4 - 16)

3.75

mero/tobra treated (n = 45)

12.8 ± 3.6

13

21 (6 - 27)

3

FEV1 ≥ 70% predicted (n = 11)

11.9 ± 2.4

12

8 (7 - 15)

3

FEV1 40% - 69% predicted (n = 46)

12.3 ± 2.8

13

15 (6 - 21)

3

FEV1 < 40% predicted (n = 38)

13.2 ± 3.8

14

23 (4 - 27)

3

Time to Peak FEV 1 Measure

    

All patients

8.7 ± 4.0

10

19 (0 - 19)

6.5

ceftaz/tobra treated

8.9 ± 4.0

10

15 (1 - 16)

6.75

mero/tobra treated

8.5 ± 4.3

9

19 (0 - 19)

5

FEV1 ≥ 70% predicted

7.9 ± 3.3

7

12 (4 - 15)

5

FEV1 40% - 69% predicted

8.0 ± 4.2

9.5

15 (0 - 15)

6

FEV1 < 40% predicted

9.9 ± 3.6

10

16 (3 - 19)

4.75