Table 2 Factors involved in the bronchial vasculature remodelling in asthma and COPD
From: The role of the bronchial microvasculature in the airway remodelling in asthma and COPD
Angiogenesis | Vasodilatation | Permeability |
|---|---|---|
VEGF | VEGF | VEGF |
FGF | Histamine | Histamine |
TGFβ | Heparine | Adenosin |
HGF | Tryptase | Bradychinin |
HIF | NO | Ang-1, Ang-2 |
Ang-1 | TGFα, TGFβ | SP |
Histamine | FGF | CGRP |
PGD2 | EGF | LTB4, LTC4, LTD4 |
PGI2 | IL-4 | PAF |
LTC2 | TNFα | ET-1 |
PAF | LTC4 | TNFα |
SP | PGD2 | ECP |
VIP | Â | Â |
IL-8, IL-13 | Â | Â |
TNFα |  |  |
NKA | Â | Â |
Angiogenin | Â | Â |
MMPs | Â | Â |
IGF-1 | Â | Â |
Chymase | Â | Â |
VCAM-1 | Â | Â |
E-selectin | Â | Â |
αvβ3 |  |  |