Table 1 Effects of nicotine on des-Arg⁹-bradykinin- and bradykinin-induced airway contractions

Day 1

0 (Ctrl)

17

1.21 ± 0.19

6.49 ± 0.12

15

0.99 ± 0.18

5.81 ± 0.13

10

18

1.33 ± 0.17

6.52 ± 0.11

16

1.29 ± 0.16

5.79 ± 0.18

Day 2

0 (Ctrl)

16

1.47 ± 0.19

6.56 ± 0.14

17

1.51 ± 0.23

6.15 ± 0.27

10

16

1.52 ± 0.19

6.94 ± 0.13

17

1.86 ± 0.19

6.75 ± 0.35

Day 4

0 (Ctrl)

18

1.16 ± 0.13

6.96 ± 0.19

21

1.40 ± 0.20

6.72 ± 0.38

1

16

1.89 ± 0.26

6.28 ± 0.50

19

2.10 ± 0.34

6.57 ± 0.36

10

21

2.04 ± 0.25 **

7.20 ± 0.20

22

2.18 ± 0.26 *

7.30 ± 0.25