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Table 1 Genes identified from individual studies

From: Asthma susceptible genes in Chinese population: A meta-analysis

Gene Chromosome location of gene Polymorphism Aminoacid change Genetic model Genotypes Evaluated Other genotypes Cases Controls
β2-AR 5q31-32 -46G/A Arg16Gly Recessive GG GA+AA 1796 1589
   -79G/C Gln27Glu Recessive GG GC+CC 823 692
IL-4R 16p11.2-12.1 -1902G/A Q576R Dominant GG+GA AA 2308 1971
   -223G/A Ile/Val Recessive GG GA+AA 1623 1304
IL-4 5q31 -589C/T   Dominant CC+CT TT 1724 1656
TNF-α 6p21.1-21.3 -308A/G   Dominant AA+AG GG 1428 1511
FcεRIβ 11q13 -6843G/A Glu237Gly Dominant GG+GA AA 1434 1276
   -109C/T   Recessive CC CT+TT 428 371
ACE 17q23 D/I   Recessive DD DI+II 385 335
IL-13 5q31 -2044A/G Gln130Arg Dominant AA+AG GG 1512 1351
   -1923C/T   Recessive TT CC+CT 645 588
IL-1β 2q12-21 -511C/T   Dominant TT+TC CC 333 255
LT-α 6q21.3 +252A/G   Dominant GG+GA AA 674 896
TGF-β1 19q13 -509C/T   Dominant TT+TC CC 406 390
CD14 5q31.1 -159C/T   Dominant TT+TC CC 1381 1219
ADAM33 20p13 T1 Met764Thr Recessive CC TT+TC 569 512
RANTES 17q11.2-12 -28G/C   Dominant GG+GC CC 314 229
   -403A/G   Dominant AA+AG GG 343 205