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Table 3 Characteristics of the controls, COPD and IPF patients in the immunohistochemical analyses of the lung

From: Hemoglobin α and β are ubiquitous in the human lung, decline in idiopathic pulmonary fibrosis but not in COPD

 

Control

COPD

Stage IV

IPF

Patients, n

6

7

7

Age, yr

64 ± 3

60 ± 2

61 ± 3

Sex, M/F

5/1

4/3

7/0

Pack years, yr

10 ± 7 *

35 ± 5**

15 ± 9 ***

FEV1 (%)

105 ± 5

40 ± 9 ****

60 ± 8****

FVC (%)

104 ± 6

59 ± 6****

57 ± 7****

  1. Data are presented as mean ± SEM.
  2. * Two of the controls were never smokers and four of the controls had smoked 10-30 years but stopped smoking at least 2 years before study.
  3. ** The patients were ex-smokers, but had stopped smoking at least 2 years before the study.
  4. *** Three of the IPF patients were never smokers, four had smoked 15-45 years but stopped smoking at least two years before the study.
  5. **** p < 0.05 versus control subjects.