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Figure 3 | Respiratory Research

Figure 3

From: Pharmacotherapy in pulmonary arterial hypertension: a systematic review and meta-analysis

Figure 3

Relationship between mortality rate and functional class severity in individual trials. Relationship between the relative risk of mortality with prostanoid treatment compared to placebo and the proportion of patients in each trial with functional class III or IV symptoms (weighted linear regression). Studies with a greater proportion of functional class III or IV patients showed a greater reduction in mortality (R2 = 0.5093). Shaded circles represent studies of intravenous prostanoids.

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