Figure 5
The in silico networks inferred by PPI Spider and KEGG Spider. The proteins identified in the proteomic study are marked by rectangles, and red nodes represent the proteins involved in glycolysis. (A) The PPI Spider network model covers 16 identified proteins. The intermediate proteins not detected in the proteomic study are marked by circles and the corresponding Entrez gene IDs: 25139, GLUT4 (solute carrier family 2 [facilitated glucose transporter], member 4); 24413, NR3C1 (glucocorticoid receptor); 58945, DYNLL1 (dynein light chain 1, cytoplasmic); and 117282, hnRNP K (heterogeneous nuclear ribonucleoprotein K). (B) The KEGG Spider network model covers eight identified proteins. The intermediate proteins not detected in the proteomic study are marked by triangles and the corresponding Entrez gene ID: 85260, ENTPD6 (ectonucleoside triphosphate diphosphohydrolase 6). The chemical compounds involved are marked with circles.