Table 1 Patient Characteristics
From: Can AMP induce sputum eosinophils, even in subjects with complete asthma remission?
Complete remission | Current asthma | |||
|---|---|---|---|---|
(n = 7) | Total group (n = 23) | Negative PC 20 AMP (n = 12) | Positive PC 20 AMP (n = 11) | |
Sex (M/F) | 2/5 | 14/9 | 6/6 | 8/3 |
Age (years) | 53.0 (32 - 67) | 48.0 (35 - 70) | 47.5 (35 - 70) | 48.0 (38 - 62) |
FEV1 (% predicted) | 108.0 (102 - 144)*,‡‡ | 97 (76 - 131) | 96.2 (76.2 - 123) | 96.5 (84.8 - 131) |
PC20 AMP (mg/ml) | >320 | >320 (0.02 - >320) | >320 | 12.0 (0.02 - 174) |
Cumulative AMP dose (mg) | 639.99 | 639.99 (0.02 - 639.99) | 639.99 | 39.99 (0.02 - 639.99) |
PC20 Histamine (mg/ml) | >32.0 | N.A. | 16.9 (2.5 - 32.0) | N.A. |
Reversibility FEV1 (%) | 4.59 (1.76 - 9.72) | 5.42 (-2.98 - 26.7) | 3.15 (-2.98 - 12.2)‡ | 9.40 (1.76 - 26.7) |
IgE (IU/L) | 47 (7 - 166) | 66 (11 - 558) | 61 (14 - 246) | 78 (11 - 558) |
Positive Phadiatop (n (%)) | 3 (43)‡ | 15 (65) | 5 (42)‡ | 10 (91) |
Eosinophils blood (× 109/L) | 0.12 (0.09 - 0.24) | 0.15 (0.03 - 0.35) | 0.11 (0.03 - 0.35) | 0.17 (0.07 - 0.25) |