Table 1 Characteristics of the subjects in the Saguenay_Lac-Saint-Jean study.
From: Asthma and genes encoding components of the vitamin D pathway
| Â | All subjects (n = 1064) | Probands (n = 210) | Affected members (n = 320) | Unaffected members (n = 534) |
|---|---|---|---|---|
Age (years) | 39.7 ± 22.1 | 17.6 ± 9.4 | 40.0 ± 19.5 | 48.3 ± 21.1 |
Male: Female ratio | 0.80 | 0.86 | 0.68 | 0.85 |
Mean age of onset (years) | 16.5 ± 17.0 | 7.4 ± 7.6 | 22.3 ± 18.7 | NA |
FEV1 (% predicted) | 94.1 ± 19.8 | 92.5 ± 16.1 | 88.9 ± 23.2 | 99.1 ± 17.2 |
PEFR (%) | 6.4 ± 4.6 | 7.3 ± 4.2 | 7.4 ± 5.9 | 5.0 ± 2.9 |
PC20 (mg/ml) | 21.1 ± 24.9 | 5.1 ± 8.5 | 8.8 ± 15.4 | 39.4 ± 24.9 |
Serum IgE (mg/L) | 452.7 ± 1619.2 | 720.3 ± 1919.9 | 531.4 ± 1960.8 | 244.8 ± 1005.9 |
Atopy (n) | 593 (56.3%) | 171 (81.8%) | 218 (69.2%) | 204 (38.6%) |
Smoking Status (n) | Â | Â | Â | Â |
Never | 551 (52.6%) | 173 (84.0%) | 154 (48.7%) | 224 (42.7%) |
Ex-smoker | 291 (27.8%) | 11 (5.3%) | 100 (31.7%) | 180 (34.3%) |
Smoker | 205 (19.6%) | 22 (10.7%) | 62 (19.6%) | 121 (23.1%) |