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Figure 3 | Respiratory Research

Figure 3

From: Differential effects of cytokines and corticosteroids on Toll-like receptor 2 expression and activity in human airway epithelia

Figure 3

A) Effects of cytokines and dexamethasone (Dex) on TLR2-mediated IL-8 production. Epithelia were pre-treated overnight (18 hr) with cytokines (TNF-α and IFN-γ), dexamethasone, or a combination of cytokines plus dexamethasone, then exposed to Pam3CSK4 (25 μg/ml) (black), or control serum-free media (grey) for a period of 24 hours. Data represent the mean ± SEM from 5 donor samples. *P < 0.05. B) Polarity of TLR2 responses in airway epithelia. Epithelia were pre-treated overnight (18 hr) with cytokines (TNF-α and IFN-γ), then exposed to Pam3CSK4 (25 μg/ml), applied to either the apical (white) or basolateral (BL, black) surface, or control serum-free media (shown in grey) for a period of 24 hours. Data represent the mean ± SEM from 5 donor samples. *P < 0.05.

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Respiratory Research

ISSN: 1465-993X

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