Figure 3

Comparison of mRNA expression in seven candidate genes between TPCH test (n = 30, microarray) and training set (n = 62 qRT-PCR data), with two public microarray datasets of lung tissue samples (Spira et al, [12], n = 34; and Golpon et al [13], n = 10). Fold change represents mean expression ratio of moderate versus mild emphysema (TPCH training set), severe/mild emphysema versus normal (Spira et al), or severe emphysema versus normal samples (Golpon et al). The absence of a bar indicates the gene was not represented on the microarray platform.