Treatment with NF-κB decoy ODNs markedly attenuated the number of airway inflammatory cells in smoke-induced chronic airway inflammation on day 92. Total and differential cell counts were performed on the collected BALF. Data were expressed as mean ± STD (n = 8/group). Symbols delineate statistical significance compared to NS mice (*, P < 0.05) and Scr mice (#, P < 0.05). NS: normal saline-treated smoke-induced mice; Decoy: NF-κB decoy ODNs-treated smoke-induced mice; Scr: scrambled ODNs-treated smoke-induced mice.