Figure 4
From: Effects of cigarette smoke on endothelial function of pulmonary arteries in the guinea pig
Smooth muscle cell proliferation in small intrapulmonary arteries. Immunohistochemistry for α-actin in small vessels of a control guinea pig (A) and an animal exposed to cigarette smoke (CS) (B). The vessel of the exposed animal shows a thicker wall with a strong immunoreactivity to α-actin. Scale bar, 50 μm. Bar graphs show the number of vessels/mm2 with positive immunoreactivity to α-actin (C) and desmin (D) in control and CS-exposed guinea pigs, for 3 and 6 months of exposure. * p < 0.05 compared with control group. Values are mean ± SEM.