Figure 1From: Effects of cigarette smoke on endothelial function of pulmonary arteries in the guinea pig Endothelial function of pulmonary and aorta arteries. Relaxation of main pulmonary artery and aorta to cumulative doses of adenosine-5'-diphosphate (ADP) expressed as % of contraction to norepinephrine (NE). Upper panels show dose-response curves of pulmonary arteries in smoke exposed (continuous line) and control (dashed line) animals at 3 (A) and 6 months (B) of exposure. Lower panels show dose-response curves of aorta at 3 (C) and 6 months (D) of exposure. Values are mean ± SEM.Back to article page