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Figure 2 | Respiratory Research

Figure 2

From: Allergic lung inflammation alters neither susceptibility to Streptococcus pneumoniae infection nor inducibility of innate resistance in mice

Figure 2

Allergic inflammation and induced secretion affect neither survival nor pathogen burden in S. pneumoniae pneumonia. (A) Survival of ovalbumin-sensitized mice 7 days after challenge with intermediate dose (1.6 × 1010 CFU/ml) S. pneumoniae after induction of allergic inflammation by inhaled ovalbumin and/or secretion by inhaled ATP, as indicated (16 mice/group). There was no statistically significant difference in survival in any group compared to naive (OVA-, ATP-) mice. (B) Bacterial counts of lung homgenates immediately after pneumococcal challenge (1.6 × 1010 CFU/ml) of ovalbumin-sensitized mice, with or without induction of allergic inflammation and/or secretion (3 mice/group).

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Respiratory Research

ISSN: 1465-993X

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