Figure 2
From: Importin-13 genetic variation is associated with improved airway responsiveness in childhood asthma
Impact of IPO13 polymorphism rs2428953 on airway hyperresponsiveness. Mean log(methacholine PC20) values and SEM. Common genotype (CC) denoted by solid black lines, heterozygotes and TT homozygotes denoted by dashed red lines. Open circles denote placebo/nedocromil groups, closed circles represent budesonide groups. Vertical line at 0 months denotes time of randomization. Airway hyperresponsiveness was significantly different (p < 0.05) between the placebo/nedocromil subjects with CC genotype and all other subjects at all time points following randomization, as denoted by (*).