Figure 4
From: Impact of interleukin-6 on hypoxia-induced pulmonary hypertension and lung inflammation in mice
Lung macrophages recruitment under hypoxic condition in IL-6 +/+ and IL-6 -/- mice. Lung F4/80 protein levels assessed by Western blotting in IL-6+/+ mice and IL-6-/-mice after normoxia or hypoxia (n = 5 in each group) (a). Each bar is the mean ± SEM. *P < 0.05 compared to IL-6+/+ mice exposed to hypoxia of the same duration. Lung macrophage recruitment illustrated by representative photomicrographs showing F4/80 immunostaining in lung sections from IL-6+/+ and IL-6-/- mice under normoxia and hypoxia (b). Macrophages are shown by arrows.