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Figure 3 | Respiratory Research

Figure 3

From: Specific mediator inhibition by the NO donors SNP and NCX 2057 in the peripheral lung: implications for allergen-induced bronchoconstriction

Figure 3

Effect of pretreatment with different drugs compared with the control on mediator release from sensitized GPLP after challenge with 1000 ng/ml of OVA. Release of A, Histamine (ng/ml); B, CysLTs; C, LTB4; D, PGD2; E, TXB2 (pg/ml). All samples were collected at baseline and then at the plateau after 1000 ng/ml of OVA. The parenchymal strips had been pretreated for 15 min with Tyrode's solution (control), 100 μM SNP (SNP), 100 μM NCX 2057 (2057) and 100 μM ferulic acid (FA). All data are expressed as mean ± s.e.m.; statistical analysis was performed by one-way ANOVA. *, P < 0.05; **, P < 0.01; ***, P < 0.001 vs control.

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Respiratory Research

ISSN: 1465-993X

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