Table 3 Morphometric analysis of lungs from WT PBS control and poly(I:C)-treated, and TLR-3 KO PBS control and poly(I:C)-treated mice.
From: Long-term activation of TLR3 by Poly(I:C) induces inflammation and impairs lung function in mice
Group | Tissue Density % | Tissue Cellularity % | Airway Mucosal Height μm |
|---|---|---|---|
WT PBS | 32 ± 2 | 8 ± 1 | 15 ± 1 |
WT Poly(I:C) | 50 ± 5* | 16 ± 2* | 26 ± 4* |
Fold Increase (Compared to WT PBS) | 1.7 | 2 | 1.7 |
KO PBS | 36 ± 7 | 9 ± 1 | 18 ± 3 |
KO Poly(I:C) | 49 ± 6* | 14 ± 3* | 19 ± 2** |
Fold Increase (Compared to KO PBS) | 1.4 | 1.5 | NC |