Figure 1
From: Long-term activation of TLR3 by Poly(I:C) induces inflammation and impairs lung function in mice
Poly(I:C) induces a dose dependent influx of inflammatory cells into the airways of mice. Mice were administered PBS or, 10, 20, 50 or 100 μg poly(I:C) (I.N.) every 24 h for three days. 24 hours after the last administration, mice were euthanized and BALs were performed. The total number of cells (1A), neutrophils (1B) and mononuclear cells (1C) were measured in the BAL. Data are the mean ± SEM of 6–15 mice from two separate experiments. The Kruskal-Wallace test was used to compare the treatment groups. When this test showed a difference among the treatment groups, selected pairs of treatments were compared using Dunn's multiple comparison test. ** p < 0.001 when compared to PBS-treated mice.