From: Expression of transforming growth factor-β (TGF-β) in chronic idiopathic cough
Normals | Chronic cough | |
---|---|---|
Number | 13 | 20 |
Gender (Male/Female) | 9:4 | 4:16** |
Age (years) | 19.9 ± 0.4 | 55.4 ± 2.5** |
Smoking status (n) | ||
never | 12 | 11 |
ex-smoker | 1 | 9 |
Pack-years | 7 | 13.1 ± 3.5 |
GORD (n) | NA | 10 |
Postnasal drip (n) | NA | 7 |
Neither (n) | NA | 5 |
Atopy (%) | 31 | 26 |
Capsaicin (log10 C5) | ND | 0.53 ± 0.14 |
FEV1 (% predicted) | 96.0 ± 3.3 | 99.0 ± 2.3 |
FVC (% predicted) | 100.5 ± 3.3 | 96.8 ± 4.6 |
Bronchoalveolar lavage | ||
% macrophages | 97.6 ± 0.5 | 90.1 ± 2.6** |
% neutrophils | 1.5 ± 0.4 | 6.7 ± 2.6* |
% lymphocytes | 0.7 ± 0.2 | 3.0 ± 0.8** |
% eosinophils | 0.3 ± 0.1 | 0.2 ± 0.1 |