Figure 3
From: Adult onset lung disease following transient disruption of fetal stretch-induced differentiation
Changes in PV curves at 18 months of age following in-utero gene transfer at 16 days gestation. Respiratory function in 18 month old animals following treatment at 16 days gestation with replication deficient adenovirus containing eGFP, (control, solid lines), or anti-sense CFTR gene fragment, (ASCFTR, dashed lines). Four animals are included in each data point. PV curves were obtained in triplicate for each animal. All data is presented as mean ± SEM. p < 0.0001.