Table 2 Associations* between SNPs in ADAM33 gene and COPD
From: Adam33 polymorphisms are associated with COPD and lung function in long-term tobacco smokers
COPD | Controls | |||||
|---|---|---|---|---|---|---|
SNP | Genotype | N | % | N | % | p value* |
rs2853211 | GG | 16 | 5 | 20 | 6 | |
(IVS1_729) | GC | 90 | 31 | 105 | 34 | 0.4083 |
(AB+) | CC | 180 | 63 | 185 | 60 | |
rs4987245 | AA | 3 | 1 | 1 | 0 | |
(IVS1_379) | AG | 51 | 18 | 45 | 15 | 0.1522 |
GG | 231 | 81 | 261 | 85 | ||
rs570269 | GG | 14 | 05 | 10 | 3 | |
(IVS2_488) | GC | 81 | 28 | 93 | 30 | 0.736 |
CC | 190 | 67 | 205 | 66 | ||
rs487377 | AA | 15 | 3 | 11 | 5 | |
(IVS2_1141) | AG | 97 | 29 | 90 | 34 | 0.0826 |
(BC+1) | GG | 174 | 67 | 208 | 61 | |
rs2853210 | AA | 9 | 3 | 13 | 4 | |
(IVS2_421) | AG | 99 | 35 | 121 | 39 | 0.1519 |
GG | 178 | 62 | 175 | 57 | ||
rs511898 | AA | 35 | 12 | 44 | 14 | |
(IVS6_66) | AG | 116 | 41 | 136 | 44 | 0.2042 |
(F+1) | GG | 134 | 47 | 129 | 42 | |
rs3918395 | TT | 5 | 2 | 4 | 1 | |
(IVS13_35) | GT | 67 | 24 | 74 | 24 | 0.8832 |
(M+1) | GG | 212 | 75 | 231 | 75 | |
rs612709 | TT | 4 | 1 | 5 | 2 | |
(IVS16_21) | CT | 54 | 19 | 94 | 30 | 0.0028 |
(Q-1) | CC | 226 | 80 | 210 | 48 | |
rs3918396 | AA | 2 | 1 | 3 | 1 | |
(Ile710val) | AG | 35 | 12 | 68 | 22 | 0.0025† |
(S1) | GG | 247 | 87 | 237 | 77 | |
rs528557 | CC | 17 | 6 | 27 | 9 | |
(Gly717Gly) | CG | 107 | 38 | 133 | 43 | 0.0326 |
(S2) | GG | 160 | 56 | 148 | 48 | |
rs2853209 | TT | 60 | 21 | 77 | 25 | |
(IVS19_181) | AT | 144 | 50 | 162 | 52 | 0.0921 |
AA | 81 | 28 | 70 | 23 | ||
rs598418 | CC | 38 | 13 | 31 | 10 | |
(IVS19_384) | CT | 147 | 52 | 153 | 49 | 0.1062 |
TT | 100 | 35 | 125 | 40 | ||
rs44707 | CC | 49 | 17 | 42 | 13 | |
(IVS19_427) | CA | 143 | 50 | 151 | 49 | 0.1554 |
(ST+4) | AA | 94 | 33 | 115 | 37 | |
rs574174 | AA | 7 | 2 | 12 | 4 | |
(IVS19_959) | GA | 79 | 28 | 102 | 33 | 0.0731 |
(ST+7) | GG | 199 | 70 | 196 | 63 | |
rs2280091 | CC | 6 | 2 | 5 | 1 | |
(Met738Thr) | CT | 69 | 24 | 77 | 25 | 0.8823 |
(T1) | TT | 223 | 74 | 211 | 73 | |
rs678881 | GG | 19 | 7 | 12 | 4 | |
(IVS21_143) | CG | 116 | 41 | 115 | 37 | 0.0592 |
CC | 149 | 52 | 182 | 59 | ||
rs2787094 | GG | 10 | 4 | 18 | 6 | |
(3UTR_449) | CG | 90 | 31 | 123 | 40 | 0.0068 |
(V4) | CC | 186 | 65 | 168 | 54 | |
rs543749 | AA | 2 | 1 | 4 | 1 | |
(IVS21_32) | AC | 52 | 18 | 90 | 29 | 0.0011† |
(V-1) | CC | 233 | 81 | 214 | 69 | |
rs677044 | CC | 16 | 6 | 17 | 5 | |
(3UTR_179) | TC | 99 | 35 | 98 | 32 | 0.4908 |
TT | 170 | 60 | 195 | 63 | ||