Figure 7

NFAT inhibitors, VIVIT and Cyclosporin A inhibitshypoxia-induced human PASMC proliferation. Cell proliferation wasdetected before (Basal) and after 72 h incubation under normoxia, hypoxia, hypoxia plus VIVIT (4 μM) and hypoxia plus Cyclosporin A (0.03 mg/mL) respectively. A: Phase contrast image of cultured human PASMC (×200). B: Image of DAPI stained human PASMC. C: Cell number was determined by cell counting. n = 5, ^## P < 0.01 vs. normoxia, ** P < 0.01 vs. hypoxia.