Figure 3

Inhibitory effect of sildenafil on hypoxia-induced enhancement of resting [Ca ²⁺ ] _i , CPA-induced ER release and SOC-mediated Ca ²⁺ influx. A: Representative records of resting [Ca²⁺]_i, cyclopiazonic acid (CPA)-induced ER Ca²⁺ release and SOC-mediated Ca²⁺ entry upon changing perfusion from Ca²⁺-free PSS to 1.8 mM Ca²⁺ PSS were measured in different groups. B: The statistic data of resting [Ca²⁺]_i, CPA-inducted ER release, and CCE are expressed as the mean ± SEM. ^### P < 0.001 vs. normoxia, * P < 0.05 vs. hypoxia, *** P < 0.001 vs. hypoxia.