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Table 4 TaqMan RT-PCR Confirmation of Smoking Responsive Genes in Small Airway Epithelium and Alveolar Macrophages

From: Disparate oxidant gene expression of airway epithelium compared to alveolar macrophages in smokers

Small airway epithelium

Alveolar macrophages

Gene

Fold-change 1

p value 2

Gene

Fold-change

p value

Alcohol dehydrogenase 7

6.2

< 0.02

Superoxide dismutase 2

-3.6

< 0.03

Glutathione peroxidase 2

3.9

< 0.01

Glutamate cysteine ligase C

3.8

< 0.01

Metallothionein 1F

-2.3

< 0.05

Protein kinase C alpha

4.2

< 0.01

Cytochrome P450 1B1

36.7

< 0.03

   
  1. 1 Fold change is calculated as the average expression level in healthy smokers (n = 6) compared to the average expression level in healthy nonsmokers (n = 6).
  2. 2 p value calculated using an unpaired t test assuming unequal variance.
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Respiratory Research

ISSN: 1465-993X

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