Figure 4

There was a correlation between numbers of fibrocytes and percentage of tissue in alveolar parenchyme, total area of the endothelial layer, and total area of the lumen. Panels a-c represent correlations between percentage of tissue in alveolar parenchyma and number of fibrocytes stained with markers CXCR4 and prolyl 4-hydroxylase (R = 0.7363; p < 0.01) (a), CD45R0 and prolyl 4-hydroxylase (R = 0.6220; p < 0.05) (b), and CD34 and prolyl 4-hydroxylase (R = 0.6220; p < 0.05) (c). Panels d-f represent correlations between percentage endothelial layer (of total area of tissue) and number of fibrocytes stained with markers CXCR4 and prolyl 4-hydroxylase (R = 0.8044; p < 0.001) (d), CD45R0 and prolyl 4-hydroxylase (R = 0.8420; p < 0.001) (e), and CD34 and prolyl 4-hydroxylase (R = 0.7426; p < 0.01) (f). Panels g-i represent correlations between percentage vessel lumen (of total area of tissue) and number of fibrocytes stained with markers CXCR4 and prolyl 4-hydroxylase (R = 0.7503; p < 0.01) (g), CD45R0 and prolyl 4-hydroxylase (R = 0.8339; p < 0.001) (h), and CD34 and prolyl 4-hydroxylase (R = 0.7085; p < 0.01) (i). Prolyl 4-hydroxylase is indicated as P4-OH. Lung transplanted, closed circle; bone marrow transplanted, open circle; control, circle with dot.