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Fig. 7 | Respiratory Research

Fig. 7

From: Dectin-1 aggravates neutrophil inflammation through caspase-11/4-mediated macrophage pyroptosis in asthma

Fig. 7

Positive correlation between macrophage Dectin-1 and neutrophils in asthma patients. Induced sputum of 33 asthma patients and 10 healthy controls was collected. A Flow gating strategy for macrophages, neutrophils, eosinophils in sputum of asthma patients, and MFI of Dectin-1 on macrophages. B Calculation of the MFI of Dectin-1 on induced sputum macrophages of healthy and asthma groups. C–F The correlation between MFI of macrophage Dectin-1 and sputum Neu%, sputum EOS%, blood neu count, blood eos count of asthma group. G–J Analysis of the difference between low Dectin-1 and high Dectin-1 expression groups of asthma (Sputum Neu%: proportion of neutrophils in induced sputum; sputum EOS%: proportion of eosinophils in induced sputum; blood neu count: peripheral blood neutrophil count; blood eos count: peripheral blood eosinophil count). ( *P < 0.01,**P < 0.05, two-tailed paired Student’s t test, spearman rank correlation, error bars represent mean ± SD)

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