Fig. 6
From: FGF18 alleviates sepsis-induced acute lung injury by inhibiting the NF-κB pathway
FGF18 promotes lung repair and attenuates HUVEC injury by inhibiting the NF-κB pathway. (A) HUVECs were subjected to western blotting analysis. The expression of p-p65, p65, p-IκBα, and IκBα were detected. (n = 5 per group). (B) C57BL/6J mice were treated with AAV-FGF18 and AAV-LacZ in the presence of LPS and then subjected to western blotting analysis. (n = 5 per group). (C) HUVECs were subjected to western blotting analysis. The expression of p-p65, p65, p-IκBα, and IκBα were detected. (n = 5 per group). (D) Immunofluorescent staining of p65 (red) and DAPI (blue) in HUVECs were detected. (n = 5 per group, Scale bar = 50 μm). (E) Immunofluorescent staining of p65 (red) and DAPI (blue) in HUVECs were detected. (n = 5 per group, Scale bar = 50 μm)