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Table 1 Baseline characteristics

From: Atorvastatin for reduction of 28-day mortality in severe and critical COVID-19 patients: a randomized controlled trial

 

Group A

(n = 110)

Group B

(n = 110)

Age

61.4 (13)

60.8 (12.7)

Male no. (%)

51 (46.4%)

45 (40.9%)

Weight (kg)

76.7 (12)

74 (10.7)

Not SARS-CoV-2 vaccinated

105 (98.1%)

107 (98.2%)

Critical cases on admission

21 (19.1%)

20 (18.2%)

WHO score on admission

5 (5–6)

5 (5–6)

Smokers

16 (14.5%)

13 (11.8%)

CLD

8 (7.4%)

7 (6.5%)

Hypertension

50 (45.9%)

46 (41.8%)

Cardiac disease

14 (13%)

13 (11.8%)

Diabetes mellitus

46 (42.6%)

39 (35.8%)

ESLD

9 (8.5%)

10 (9.1%)

ESRD

2 (1.8%)

1 (0.9%)

Neurological disease

6 (5.6%)

5 (4.6%)

Basal GCS

15 (15–15)

15 (15–15)

Basal SOFA

2 (1–3)

2 (1–3)

AST (U/L)

40 (25.25–59.5)

36 (25.5– 51.5)

ALT (U/L)

33 (18–61.75)

31 (17–52)

Total Bilirubin (mg/dL)

0.54 (0.33–78)

0.46 (0.36–0.7)

INR

1.1 (1.01–1.22)

1.13 (1.03 –1.22)

Albumin (g/dL)

3.2 (2.9–3.5)

3.1 (2.9–3.5)

S.Cr (mg/dL)

0.96 (0.8–1.25)

0.9 (0.7–1.27)

CK (IU/L)

75 (40–187.5)

61 (36–163.5)

Hemoglobin (g/dL)

12.8 (11.54–13.9)

12.48 (11.17–13.83)

TLC (103/µL)

7.9 (5.79–9.97)

8.93 (5.94–12.68)

Lymph (103/µL)

0.83 (0.52–1.14)

0.92 (0.59–1.51)

Platelets (103/µL)

197.5 (135.5–265.55)

211.5 (149.75–284)

LDH (IU/L)

311.5 (254–407.75)

369 (252.25–509.5)

D-dimer (g/L)

0.2 (0–0.3)

0.2 (0–0.4)

CRP (mg/L)

96 (44–143)

96 (27–129)

Ferritin (µg/L)

514.5 (315.5–543.5)

529 (370–546)

  1. Data presented as mean (SD), median (P25th–P75th), or number (%)
  2. Group A: Atorvastatin group; Group B: Placebo group; Cardiac disease: history of Atrial fibrillation of Ischemic heart not on Statins; ESLD: End stage Liver Disease; ESRD: End Stage Renal Disease; CLD: Chronic Lung Disease—COPD or Bronchial Asthma; GCS: Glasgow Coma Score; SOFA: Sequential Organ Failure Assessment; Neurological disease implies dementia, stroke, multiple sclerosis, Parkinson, or psychosis; AST: Aspartate Transaminase; ALT: Alanine Transaminase; INR: International Normalized Ratio; S.Cr: Serum creatinine; CK: Creatine kinase; TLC: Total Leucocytic count; LDH: Lactate Dehydrogenase; CRP: C-Reactive protein