Table 4 Stratified analysis for the associations between blood Cd and prognostic outcomes

Age (years)

  ≤ 74.0

0.136 (0.013, 1.419)

0.358 (0.065, 1.981)

1.745 (0.366, 8.318)

5.873 (0.529, 65.172)

  > 74.0

0.659 (0.058, 7.437)

0.013 (0.002, 73.445)

1.327 (1.129, 9.819)

5.502 (1.169, 25.900)

 P_interaction

0.365

0.254

0.032

0.045

Sex

 Male

0.307 (0.067, 1.410)

0.324 (0.079, 1.339)

1.748 (1.024, 5.829)

3.358 (1.139, 9.903)

 Female

1.201 (0.325, 2.541)

0.651 (0.205, 1.587)

1.225 (1.005, 4.638)

2.025 (0.895, 5.625)

 P_interaction

0.958

0.356

0.236

0.524

Smoking amount (n)

  ≤ 40.0

4.513 (0.408, 49.919)

0.918 (0.123, 6.832)

1.809 (1.209, 15.670)

9.811 (1.317, 73.0587)

  > 40.0

2.603 (0.306, 22.167)

1.112 (0.658, 2.541)

0.105 (0.003, 3.188)

6.966 (1.711, 68.224)

 P_interaction

0.524

0.098

0.086

0.044

Hypertension

Yes

1.052 (0.652, 2.365)

1.849 (0.002, 5.628)

5.431 (0.265, 7.958)

3.360 (0.001, 8.954)

No

20.238 (0.333, 128.880)

13.737 (0.423, 446.354)

0.394 (0.043, 3.632)

5.119 (1.831, 31.526)

P_interaction

0.632

0.452

0.254

0.254

Diabetes mellitus

 Yes

2.677 (0.652, 4.857)

1.125 (0.658, 4.852)

1.115 (0.777, 5.834)

2.855 (1.125, 9.562)

 No

2.555 (0.404, 16.172)

1.438 (0.262, 7.9801)

1.459 (1.289, 6.396)

3.660 (1.440, 15.953)

 P_interaction

0.325

0.258

0.043

0.036

Coronary disease

 Yes

8.315 (0.652, 13.658)

1.258 (0.687, 2.641)

1.362 (1.112, 3.658)

1.121 (0.958, 3.521)

 No

3.260 (0.433, 24.531)

1.438 (0.923, 1.240)

0.736 (0.156, 3.461)

3.691 (1.169, 15.679)

 P_interaction

0.154

0.325

0.365

0.859

Cerebrovascular diseases

 Yes

1.251 (0.658, 7.958)

0.658 (0.112, 4.658)

1.285 (1.058, 5.628)

1.652 (1.115, 4.987)

 No

2.911 (0.443, 19.111)

0.696 (0.127, 3.823)

1.359 (1.009, 6.396)

3.710 (1.070, 15.823)

 P_interaction

0.332

0.215

0.032

0.045

FVC (L)

  ≤ 2.15

0.999 (0.733, 2.156)

0.976 (0.265, 1.854)

0.958 (0.365, 1.254)

2.067 (1.300, 4.652)

  > 2.15

3.627 (0.587, 6.528)

0.989 (0.528, 1.547)

1.654 (0.687, 2.154)

1.339 (0.091, 29.265)

 P_interaction

0.069

0.215

0.063

0.036

FEV1 (L)

  ≤ 1.83

1.254 (0.658, 2.654)

1.125 (0.658, 1.587)

3.025 (1.115, 7.895)

2.635 (1.325, 7.854)

  > 1.83

0.969 (0.658, 2.152)

1.108 (0.778, 2.591)

2.625 (0.879, 3.654)

1.895 (1.112, 4.628)

 P_interaction

0.138

0.652

0.025

0.030

FEV1/FVC (%)

  ≤ 62.45

1.125 (0.857, 3.254)

1.168 (0.789, 2.635)

1.652 (0.658, 4.658)

2.025 (1.116, 4.258)

  > 62.45

1.254 (0.758, 2.654)

1.658 (0.857, 3.658)

1.115 (0.878, 3.652)

1.365 (0.879, 3.624)

 P_interaction

0.328

0.125

0.205

0.326

Predicted FEV1 (%)

  ≤ 54.05

1.259 (0.638, 1.698)

1.326 (0.832, 2.365)

0.788 (0.451, 8.152)

2.630 (0.154, 10.385)

  > 54.05

0.994 (0.411, 2.365)

1.111 (0.658, 2.635)

2.081 (0.658, 2.635)

1.366 (0.879, 2.920)

 P_interaction

0.268

0.360

0.428

0.365