Table 3 Recipients and donor characteristics for the year-2 MMP-9 comparative analysis
Stable (n = 79) | CLAD (n = 50) | p | Missing (%) | |
|---|---|---|---|---|
Gender male | 49 (62.0) | 32 (64.0) | 1 | 0 |
Age | 49 [31, 59] | 46.50 [27.25, 58.00] | 0.4 | 0 |
Height (cm) | 167.23 (7.44) | 168.70 (9.09) | 0.3 | 0 |
Weight (kg) | 58.37 (14.27) | 58.86 (13.64) | 0.8 | 0 |
Underlying disease | 0.06 | 0 | ||
COPD/emphysema | 34 (43.0) | 17 (34.0) | ||
Cystic fibrosis | 28 (35.4) | 19 (38.0) | ||
ILD | 16 (20.3) | 8 (16.0) | ||
Other | 1 (1.3) | 6 (12.0) | ||
Bacterial colo. pre Tx | 42 (53.2) | 28 (56.0) | 0.9 | 0 |
S. Aureus colo. pre Tx | 13 (16.5) | 7 (14.0) | 0.9 | 0 |
P. Aeruginosa colo. pre Tx | 21 (27) | 23 (46) | 0.04 | 0 |
Fungal colo. pre Tx | 40 (50.6) | 22 (44.0) | 0.6 | 0 |
A. fumigatus colo. pre Tx | 14 (17.7) | 11 (22.0) | 0.7 | 0 |
C. Albicans colo. pre Tx | 29 (37) | 8 (16) | 0.02 | 0 |
DSA pre TX | 17 (27.9) | 15 (36.6) | 0.5 | 20.9 |
High emergency | 9 (11.4) | 2 (4.0) | 0.2 | 0 |
Procedure | 12 (15.6) | 8 (16.3) | 1 | 2.3 |
Double lung | ||||
Heart and lung | ||||
Single lung | ||||
Surgical approach | 0.6 | 1.6 | ||
Clam shell | 15 (19.2) | 8 (16.3) | ||
Sternotomy | 1 (1.3) | 2 (4.1) | ||
Thoracotomy | 62 (79.5) | 39 (79.6) | ||
ECLS | 36 (46.8) | 22 (44.0) | 0.9 | 1.6 |
Cold ischemia (min) | 330 [275, 380] | 340 [260, 395] | 0.8 | 2.3 |
Donor age | 44 [26, 53] | 46 [36, 57] | 0.3 | 0 |
Donor gender male | 45 (57) | 33 (66) | 0.4 | 0 |
Donor smoking habit | 28 (35.4) | 19 (38.8) | 0.8 | 0.8 |
PaO2/FiO2 | 393.27 (104.85) | 392.46 (96.27) | 1 | 1.6 |
Mismatch CMV | 17 (21.5) | 11 (22.0) | 1 | 0 |
Mismatch EBV | 6 (7.6) | 8 (16.0) | 0.2 | 0 |
Dialysis | 4 (5.3) | 3 (6.1) | 1 | 3.9 |
Induction treatment | 63 (79.7) | 37 (74.0) | 0.6 | 0 |
Type of induction | 0.4 | 0 | ||
Anti-IL2 | 28 (35.4) | 12 (24.0) | ||
ATG | 35 (44.3) | 25 (50.0) | ||
None | 16 (20.3) | 13 (26.0) | ||
Resp bacterial inf post Tx | 0.1 | 0 | ||
0 | 13 (16.5) | 11 (22.0) | ||
1 | 32 (40.5) | 14 (28.0) | ||
2 | 24 (30.4) | 12 (24.0) | ||
3 | 10 (12.7) | 13 (26.0) | ||
Resp fungal inf post Tx | 0.3 | 0 | ||
0 | 46 (58.2) | 21 (42.0) | ||
1 | 23 (29.1) | 19 (38.0) | ||
2 | 8 (10.1) | 7 (14.0) | ||
3 | 2 (2.5) | 3 (6.0) | ||
Resp viral inf post Tx | 0.1 | 0 | ||
0 | 55 (69.6) | 25 (50.0) | ||
1 | 18 (22.8) | 19 (38.0) | ||
2 | 4 (5.1) | 5 (10.0) | ||
3 | 2 (2.5) | 1 (2.0) | ||
ACR (≥ 1) | 24 (30.4) | 22 (44.0) | 0.2 | 0 |
AMR | 4 (5.1) | 3 (6.0) | 1 | 0 |