Table 1 Recipients and donor characteristics for the year-1 MMP-9 comparative analysis
Stable (n = 104) | CLAD (n = 86) | p value | Missing value (%) | |
|---|---|---|---|---|
Gender male | 61 (58.7) | 45 (52.3) | 0.5 | 0 |
Age | 52 [36, 60] | 51 [28, 58] | 0.4 | 0 |
Height (cm) | 168 (8) | 165 (8) | 0.05 | 0.5 |
Weight (kg) | 61(15) | 59 (13) | 0.3 | 0.5 |
Underlying disease | 0.01 | 0 | ||
COPD/emphysema | 55 (52.9) | 33 (38.4) | ||
Cystic fibrosis | 30 (28.8) | 23 (26.7) | ||
ILD | 16 (15.4) | 17 (19.8) | ||
Other | 3 (2.9) | 13 (15.1) | ||
Bacterial colo. pre Tx | 51 (49.0) | 43 (50.0) | 1 | 0 |
Fungal colo. pre Tx | 55 (52.9) | 39 (45.3) | 0.4 | 0 |
C. Albicans colo. pre Tx | 37 (35.6) | 18 (20.9) | 0.04 | 0 |
DSA pre Tx | 19 (24.7) | 21 (32.8) | 0.4 | 25.8 |
High emergency | 8 (7.7) | 6 (7.0) | 1 | 0 |
Procedure | 0.3 | 1.1 | ||
Double lung | 87 (84.5) | 70 (82.4) | ||
Heart and lung | 0 (0.0) | 2 (2.4) | ||
Single lung | 16 (15.5) | 13 (15.3) | ||
Surgical approach | 0.2 | 4.7 | ||
Clam shell | 18 (18.2) | 8 (9.8) | ||
Sternotomy | 2 (2.0) | 4 (4.9) | ||
Thoracotomy | 79 (79.8) | 70 (85.4) | ||
ECLS | 42 (42.0) | 30 (35.7) | 0.5 | 3.2 |
Graft cold ischemia (min) | 322 [270, 380] | 345 [280, 405] | 0.12 | 3.7 |
Donor age | 44 [30, 54] | 46 [25, 57] | 0.7 | 0.5 |
Donor gender male | 62 (59.6) | 53 (62.4) | 0.8 | 0.5 |
Donor smoking habit | 37 (35.9) | 30 (36.6) | 1 | 2.6 |
PaO2/FiO2 | 400 (106) | 380 (107) | 0.2 | 0.5 |
Mismatch CMV | 16 (15.4) | 16 (18.6) | 0.7 | 0 |
Mismatch EBV | 6 (5.8) | 7 (8.1) | 0.7 | 0 |
Dialysis | 5 (5.1) | 2 (2.4) | 0.6 | 3.7 |
Induction treatment | 87 (83.7) | 60 (69.8) | 0.03 | 0 |
Type of Induction | 0.03 | 0 | ||
Anti-IL2 | 36 (34.6) | 20 (23.3) | ||
ATG | 51 (49.0) | 39 (45.3) | ||
None | 17 (16.3) | 27 (31.4) | ||
Resp bacterial inf post Tx | 0.3 | 0 | ||
0 | 19 (18.3) | 21 (24.4) | ||
1 | 40 (38.5) | 24 (27.9) | ||
2 | 31 (29.8) | 24 (27.9) | ||
3 | 14 (13.5) | 17 (19.8) | ||
Resp fungal inf post Tx | 0.7 | 0 | ||
0 | 55 (52.9) | 43 (50.0) | ||
1 | 34 (32.7) | 34 (39.5) | ||
2 | 12 (11.5) | 7 (8.1) | ||
3 | 3 (2.9) | 2 (2.3) | ||
Resp viral inf post Tx | 0.3 | 0 | ||
0 | 66 (63.5) | 50 (58.1) | ||
1 | 28 (26.9) | 25 (29.1) | ||
2 | 6 (5.8) | 10 (11.6) | ||
3 | 4 (3.8) | 1 (1.2) | ||
ACR (≥ 1) | 31 (29.8) | 37 (43.0) | 0.08 | 0 |
AMR | 3 (2.9) | 7 (8.1) | 0.2 | 0 |